TGFβ RI Polyclonal Antibody

产品详情

产品名称

TGFβ RI Polyclonal Antibody

产品货号

YM-A20681

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IF,ELISA

分子量

56kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:20000;IF 1:100-300;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human TGF beta Receptor I. AA range:131-180

特异性

TGFβ RI Polyclonal Antibody detects endogenous levels of TGFβ RI protein.

基因名称

TGFBR1

蛋白名称

TGF-beta receptor type-1

别名

TGFBR1;ALK5;SKR4;TGF-beta receptor type-1;TGFR-1;Activin A receptor type II-like protein kinase of 53kD;Activin receptor-like kinase 5;ALK-5;ALK5;Serine/threonine-protein kinase receptor R4;SKR4;TGF-beta type I receptor;Transfor

基因ID-1

7046

SwissProt

P36897

背景

The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008],

细胞定位

Cell membrane ; Single-pass type I membrane protein . Cell junction, tight junction . Cell surface . Membrane raft .