TGR5 Polyclonal Antibody

产品详情

产品名称

TGR5 Polyclonal Antibody

产品货号

YM-A20687

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

WB,ELISA,IHC

分子量

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human GPBAR. AA range:11-60

特异性

TGR5 Polyclonal Antibody detects endogenous levels of TGR5 protein.

基因名称

GPBAR1

蛋白名称

G-protein coupled bile acid receptor 1

别名

GPBAR1;TGR5;G-protein coupled bile acid receptor 1;G-protein coupled receptor GPCR19;hGPCR19;Membrane-type receptor for bile acids;M-BAR;hBG37;BG37

基因ID-1

151306

SwissProt

Q8TDU6

背景

This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008],

细胞定位

Cell membrane ; Multi-pass membrane protein .