TMPRSS3 Polyclonal Antibody

产品详情

产品名称

TMPRSS3 Polyclonal Antibody

产品货号

YM-A20732

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,IHC,IF,ELISA

分子量

49kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human TMPRSS3. AA range:405-454

特异性

TMPRSS3 Polyclonal Antibody detects endogenous levels of TMPRSS3 protein.

基因名称

TMPRSS3

蛋白名称

Transmembrane protease serine 3

别名

TMPRSS3;ECHOS1;TADG12;Transmembrane protease serine 3;Serine protease TADG-12;Tumor-associated differentially-expressed gene 12 protein

基因ID-1

64699

SwissProt

P57727

背景

This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, an LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor-associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012],

细胞定位

Endoplasmic reticulum membrane ; Single-pass type II membrane protein .