TRIM3 Polyclonal Antibody

产品详情

产品名称

TRIM3 Polyclonal Antibody

产品货号

YM-A20782

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IF,ELISA

分子量

81kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human TRIM3. AA range:1-50

特异性

TRIM3 Polyclonal Antibody detects endogenous levels of TRIM3 protein.

基因名称

TRIM3

蛋白名称

Tripartite motif-containing protein 3

别名

TRIM3;BERP;RNF22;RNF97;Tripartite motif-containing protein 3;Brain-expressed RING finger protein;RING finger protein 22;RING finger protein 97

基因ID-1

10612

SwissProt

O75382

背景

The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport. Alternatively spliced transcript variants encoding the same isoform have been identified. [provided by RefSeq, Jul 2008],

细胞定位

Cytoplasm . Early endosome . Golgi apparatus, trans-Golgi network . Cell projection, dendrite .