Tubulin α-3C/D/E Polyclonal Antibody

产品详情

产品名称

Tubulin α-3C/D/E Polyclonal Antibody

产品货号

YM-A20825

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,ELISA

分子量

50kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human TUBA3C/E. AA range:201-250

特异性

Tubulin α-3C/D/E Polyclonal Antibody detects endogenous levels of Tubulin α-3C/D/E protein.

基因名称

TUBA3C/D/TUBA3E

蛋白名称

Tubulin alpha-3C/D chain/Tubulin alpha-3E chain

别名

TUBA3C;TUBA2;TUBA3D;Tubulin alpha-3C/D chain;Alpha-tubulin 2;Alpha-tubulin 3C/D;Tubulin alpha-2 chain;TUBA3E;Tubulin alpha-3E chain;Alpha-tubulin 3E

基因ID-1

113457;7278;112714

SwissProt

Q13748;Q6PEY2

背景

Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene is an alpha tubulin gene that encodes a protein 99% identical to the mouse testis-specific Tuba3 and Tuba7 gene products. This gene is located in the 13q11 region, which is associated with the genetic diseases Clouston hidrotic ectodermal dysplasia and Kabuki syndrome. [provid

细胞定位

nucleus,cytoplasm,microtubule,