UBA2 Polyclonal Antibody

产品详情

产品名称

UBA2 Polyclonal Antibody

产品货号

YM-A20840

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,IHC,IF,ELISA

分子量

71kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human Uba2. AA range:591-640

特异性

UBA2 Polyclonal Antibody detects endogenous levels of UBA2 protein.

基因名称

UBA2

蛋白名称

SUMO-activating enzyme subunit 2

别名

UBA2;SAE2;UBLE1B;HRIHFB2115;SUMO-activating enzyme subunit 2;Anthracycline-associated resistance ARX;Ubiquitin-like 1-activating enzyme E1B

基因ID-1

10054

SwissProt

Q9UBT2

背景

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010],

细胞定位

Cytoplasm. Nucleus. Shuttles between the cytoplasm and the nucleus, sumoylation is required either for nuclear translocation or nuclear retention.