UBE1L Polyclonal Antibody

产品详情

产品名称

UBE1L Polyclonal Antibody

产品货号

YM-A20843

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,IHC,IF,ELISA

分子量

112kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human UBE1L. AA range:963-1012

特异性

UBE1L Polyclonal Antibody detects endogenous levels of UBE1L protein.

基因名称

UBA7

蛋白名称

Ubiquitin-like modifier-activating enzyme 7

别名

UBA7;UBE1L;UBE2;Ubiquitin-like modifier-activating enzyme 7;Ubiquitin-activating enzyme 7;D8;Ubiquitin-activating enzyme E1 homolog

基因ID-1

7318

SwissProt

P41226

背景

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. [provided by RefSeq, Jul 2008],

细胞定位

nucleus,nucleoplasm,cytosol,