V-ATPase B1 Polyclonal Antibody

产品详情

产品名称

V-ATPase B1 Polyclonal Antibody

产品货号

YM-A20902

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,IHC,IF,ELISA

分子量

60kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human ATP6V1B1. AA range:381-430

特异性

V-ATPase B1 Polyclonal Antibody detects endogenous levels of V-ATPase B1 protein.

基因名称

ATP6V1B1

蛋白名称

V-type proton ATPase subunit B kidney isoform

别名

ATP6V1B1;ATP6B1;VATB;VPP3;V-type proton ATPase subunit B;kidney isoform;V-ATPase subunit B 1;Endomembrane proton pump 58 kDa subunit;Vacuolar proton pump subunit B 1

基因ID-1

525

SwissProt

P15313

背景

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found i

细胞定位

Apical cell membrane . Basolateral cell membrane .