V-ATPase C2 Polyclonal Antibody

产品详情

产品名称

V-ATPase C2 Polyclonal Antibody

产品货号

YM-A20903

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

WB,ELISA

分子量

48kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human ATP6V1C2. AA range:121-170

特异性

V-ATPase C2 Polyclonal Antibody detects endogenous levels of V-ATPase C2 protein.

基因名称

ATP6V1C2

蛋白名称

V-type proton ATPase subunit C 2

别名

ATP6V1C2;V-type proton ATPase subunit C 2;V-ATPase subunit C 2;Vacuolar proton pump subunit C 2

基因ID-1

245973

SwissProt

Q8NEY4

背景

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A,three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms. [provided by RefSeq, Jul 2008],

细胞定位

vacuolar proton-transporting V-type ATPase, V1 domain,lysosomal membrane,cytosol,proton-transporting V-type ATPase, V1 domain,extracellular exosome,