Vav3 Polyclonal Antibody

产品详情

产品名称

Vav3 Polyclonal Antibody

产品货号

YM-A20909

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,ELISA

分子量

98kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human VAV3. AA range:139-188

特异性

Vav3 Polyclonal Antibody detects endogenous levels of Vav3 protein.

基因名称

VAV3

蛋白名称

Guanine nucleotide exchange factor VAV3

别名

VAV3;Guanine nucleotide exchange factor VAV3;VAV-3

基因ID-1

10451

SwissProt

Q9UKW4

背景

This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],

细胞定位

intracellular,cytosol,plasma membrane,extracellular exosome,