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产品详情
产品名称
ZAC1 Polyclonal Antibody
产品货号
YM-A20964
规格
50μL;100μL
种属反应
Human
实验应用
WB,ELISA
分子量
50kD
宿主
Rabbit
同种型
IgG
修饰
Unmodified
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克降性
Polyclonal
克隆号
免疫原
The antiserum was produced against synthesized peptide derived from human PLAGL1. AA range:311-360
特异性
ZAC1 Polyclonal Antibody detects endogenous levels of ZAC1 protein.
基因名称
PLAGL1
蛋白名称
Zinc finger protein PLAGL1
别名
PLAGL1;LOT1;ZAC;Zinc finger protein PLAGL1;Lost on transformation 1;LOT-1;Pleiomorphic adenoma-like protein 1;Tumor supressor ZAC
基因ID-1
5325
SwissProt
Q9UM63
背景
This gene encodes a C2H2 zinc finger protein that functions as a suppressor of cell growth. This gene is often deleted or methylated and silenced in cancer cells. In addition, overexpression of this gene during fetal development is thought to be the causal factor for transient neonatal diabetes mellitus (TNDM). Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding two different protein isoforms. The P1 downstream promoter of this gene is imprinted, with preferential expression from the paternal allele in many tissues. [provided by RefSeq, Nov 2015],
细胞定位
Nucleus .
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