β-1,4-Gal-T5 Polyclonal Antibody

产品详情

产品名称

β-1,4-Gal-T5 Polyclonal Antibody

产品货号

YM-A21042

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,ELISA

分子量

40kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human B4GALT5. AA range:321-370

特异性

β-1,4-Gal-T5 Polyclonal Antibody detects endogenous levels of β-1,4-Gal-T5 protein.

基因名称

B4GALT5

蛋白名称

Beta-1,4-galactosyltransferase 5

别名

B4GALT5;Beta-1;4-galactosyltransferase 5;Beta-1,4-GalTase 5;Beta4Gal-T5;b4Gal-T5;Beta-1,4-GalT II;UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 5;UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 5

基因ID-1

9334

SwissProt

O43286

背景

This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The function of the enzyme encoded by this gene is not clear. This gene was previously designated as B4GALT4 but was renamed

细胞定位

Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein. Golgi apparatus . Trans cisternae of Golgi stack. .