α-SMA Polyclonal Antibody

产品详情

产品名称

α-SMA Polyclonal Antibody

产品货号

YM-A21137

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IF,ELISA

分子量

42kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from the C-terminal region of human α-SMA.

特异性

α-SMA Polyclonal Antibody detects endogenous levels of α-SMA protein.

基因名称

ACTA1/ACTA2/ACTC1

蛋白名称

Actin alpha skeletal muscle/Actin aortic smooth muscle/Actin alpha cardiac muscle 1

别名

ACTA1;ACTA;Actin, alpha skeletal muscle;Alpha-actin-1;ACTA2;ACTSA;ACTVS;GIG46;Actin, aortic smooth muscle;Alpha-actin-2;Cell growth-inhibiting gene 46 protein;ACTC1;ACTC;Actin, alpha cardiac muscle 1;Alpha-cardiac actinACTA1;ACTA;Actin, alpha skeletal muscle;Alpha-actin-1;ACTA2;ACTSA;ACTVS;GIG46;Actin, aortic smooth muscle;Alpha-actin-2;Cell growth-inhibiting gene 46 protein;ACTC1;ACTC;Actin, alpha cardiac muscle 1;Alpha-cardiac actin

基因ID-1

59

SwissProt

P68133

背景

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. [provided by RefSeq, Jul 2008],

细胞定位

Cytoplasm, cytoskeleton.