LXRα Polyclonal Antibody

产品详情

产品名称

LXRα Polyclonal Antibody

产品货号

YM-A21156

规格

50μL;100μL

种属反应

Human,Mouse,Rat,Golden hamster

实验应用

WB,IHC,IF,ELISA

分子量

50kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from the Internal region of human NR1H3. AA range:151-200

特异性

LXRα Polyclonal Antibody detects endogenous levels of LXRα protein.

基因名称

NR1H3

蛋白名称

Oxysterols receptor LXR-alpha

别名

NR1H3;LXRA;Oxysterols receptor LXR-alpha;Liver X receptor alpha;Nuclear receptor subfamily 1 group H member 3

基因ID-1

10062

SwissProt

Q13133

背景

The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],

细胞定位

Nucleus . Cytoplasm .