Siglec-5/14 Polyclonal Antibody

产品详情

产品名称

Siglec-5/14 Polyclonal Antibody

产品货号

YM-A21265

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,IHC,IF,ELISA

分子量

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from Sialic acid-binding Ig-like lectin 5/Sialic acid-binding Ig-like lectin 14 at AA range: 91-140

特异性

Siglec-5/14 Polyclonal Antibody detects endogenous levels of Siglec-5/14 protein.

基因名称

SIGLEC5/SIGLEC14

蛋白名称

Sialic acid-binding Ig-like lectin 5/Sialic acid-binding Ig-like lectin 14

别名

SIGLEC5;CD33L2;OBBP2;Sialic acid-binding Ig-like lectin 5;Siglec-5;CD33 antigen-like 2;Obesity-binding protein 2;OB-BP2;OB-binding protein 2;CD170;SIGLEC14;Sialic acid-binding Ig-like lectin 14;Siglec-14

基因ID-1

8778

SwissProt

O15389;Q08ET2

背景

This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. [provided by RefSeq, Feb 2012],

细胞定位

Membrane; Single-pass type I membrane protein.