CD207 Polyclonal Antibody

产品详情

产品名称

CD207 Polyclonal Antibody

产品货号

YM-A21270

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,ELISA

分子量

38kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from the Internal region of human CD207. AA range:61-110

特异性

CD207 Polyclonal Antibody detects endogenous levels of CD207 protein.

基因名称

CD207

蛋白名称

C-type lectin domain family 4 member K

别名

CD207;CLEC4K;C-type lectin domain family 4 member K;Langerin;CD207

基因ID-1

50489

SwissProt

Q9UJ71

背景

The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. [provided by RefSeq, Aug 2010],

细胞定位

Membrane ; Single-pass type II membrane protein . Found in Birbeck granules (BGs), which are organelles consisting of superimposed and zippered membranes.