CXCR-3 Polyclonal Antibody

产品详情

产品名称

CXCR-3 Polyclonal Antibody

产品货号

YM-A21272

规格

50μL;100μL

种属反应

Human,Rat,Mouse,Pig,Chicken

实验应用

WB,IHC,IF,ELISA

分子量

37kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from the Internal region of human CXCR3. AA range:161-210

特异性

CXCR-3 Polyclonal Antibody detects endogenous levels of CXCR-3 protein.

基因名称

CXCR3

蛋白名称

C-X-C chemokine receptor type 3

别名

CXCR3;GPR9;C-X-C chemokine receptor type 3;CXC-R3;CXCR-3;CKR-L2;G protein-coupled receptor 9;Interferon-inducible protein 10 receptor;IP-10 receptor;CD183

基因ID-1

2833

SwissProt

P49682

背景

C-X-C motif chemokine receptor 3(CXCR3) Homo sapiens This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716). [provided by RefSeq, Jun 2011],

细胞定位

[Isoform 1]: Cell membrane ; Multi-pass membrane protein .; [Isoform 2]: Cell membrane ; Multi-pass membrane protein .