Keratin-pan Polyclonal Antibody

产品详情

产品名称

Keratin-pan Polyclonal Antibody

产品货号

YM-A21315

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IF,ELISA

分子量

65kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:20000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human Keratin around the non-acetylation site of Lys185 AND OTHERS. AA range:151-200

特异性

Keratin-pan Polyclonal Antibody detects endogenous levels of Keratin-pan protein.

基因名称

KRT2

蛋白名称

Keratin, type II cytoskeletal 2 epidermal

别名

KRT2;KRT76;KRT3;KRT5;KRT6A;KRT6B;KRT6C;KRT71;KRT72;KRT73;KRT74;KRT75;KRT79;KRT8;KRT84;Keratin, type II cytoskeletal 2 epidermal;Keratin, type II cytoskeletal 2 oral;Keratin, type II cytoskeletal 3;Keratin, type II cytoskeletal 5;Keratin, type II cytoskeletal 6A;Keratin, type II cytoskeletal 6B;Keratin, type II cytoskeletal 6C;Keratin, type II cytoskeletal 71;Keratin, type II cytoskeletal 72;Keratin, type II cytoskeletal 73;Keratin, type II cytoskeletal 74;

基因ID-1

3849

SwissProt

P35908

背景

keratin 2(KRT2) Homo sapiens The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008],

细胞定位

extracellular space,nucleus,cytoplasm,Golgi apparatus,intermediate filament,membrane,keratin filament,intermediate filament cytoskeleton,extracellular exosome,