HSP70 Polyclonal Antibody

产品详情

产品名称

HSP70 Polyclonal Antibody

产品货号

YM-A21388

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

IF,WB,IHC,ELISA

分子量

70kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

IF 1:50-200;WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:20000;Not yet tested in other applications;

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human HSP70 around the non-acetylation site of K246.

特异性

HSP70 Polyclonal Antibody detects endogenous levels of HSP70 protein

基因名称

HSPA1A;HSPA1B

蛋白名称

Heat shock 70 kDa protein 1A/1B

别名

HSPA1A;HSPA1;HSPA1B;Heat shock 70 kDa protein 1A/1B;Heat shock 70 kDa protein 1/2;HSP70-1/HSP70-2;HSP70.1/HSP70.2

基因ID-1

3303;3304

SwissProt

P0DMV8;P0DMV9

背景

This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 2008],

细胞定位

Cytoplasm . Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Secreted . Localized in cytoplasmic mRNP granules containing untranslated mRNAs.