EKLF Polyclonal Antibody

产品详情

产品名称

EKLF Polyclonal Antibody

产品货号

YM-A21389

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,ELISA

分子量

38kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human KLF1 around the non-acetylation site of Lys274. AA range:231-280

特异性

EKLF Polyclonal Antibody detects endogenous levels of EKLF protein only when acetylation at K274.

基因名称

KLF1

蛋白名称

Krueppel-like factor 1

别名

KLF1;EKLF;Krueppel-like factor 1;Erythroid krueppel-like transcription factor;EKLF

基因ID-1

10661

SwissProt

Q13351

背景

This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. [provided by RefSeq, Oct 2009],

细胞定位

Nucleus . Colocalizes with SUMO1 in nuclear speckles. .