SDHB Polyclonal Antibody

产品详情

产品名称

SDHB Polyclonal Antibody

产品货号

YM-A21408

规格

50μL;100μL

种属反应

Human,Mouse,Rat,Fish

实验应用

WB,IHC,IF,ELISA

分子量

31kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:20000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from the Internal region of human SDHB. AA range:131-180

特异性

SDHB Polyclonal Antibody detects endogenous levels of SDHB protein.

基因名称

SDHB

蛋白名称

Succinate dehydrogenase [ubiquinone] iron-sulfur subunit mitochondrial

别名

SDHB;SDH;SDH1;Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial;Iron-sulfur subunit of complex II;Ip

基因ID-1

6390

SwissProt

P21912

背景

Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq, Jul 2008],

细胞定位

Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.