Neuropilin Polyclonal Antibody

产品详情

产品名称

Neuropilin Polyclonal Antibody

产品货号

YM-A21410

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IF,ELISA

分子量

100kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:20000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from the Internal region of human NRP1. AA range:321-370

特异性

Neuropilin Polyclonal Antibody detects endogenous levels of Neuropilin protein.

基因名称

NRP1

蛋白名称

Neuropilin-1

别名

NRP1;NRP;VEGF165R;Neuropilin-1;Vascular endothelial cell growth factor 165 receptor;CD304

基因ID-1

8829

SwissProt

O14786

背景

This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011],

细胞定位

[Isoform 2]: Secreted .; Mitochondrion membrane ; Single-pass type I membrane protein . Cell membrane ; Single-pass type I membrane protein . Cytoplasm .