ZNF384 Polyclonal Antibody

产品详情

产品名称

ZNF384 Polyclonal Antibody

产品货号

YM-A21471

规格

50μL;100μL

种属反应

Human,Rat

实验应用

WB,ELISA

分子量

64kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from the N-terminal region of human ZNF384. AA range:1-50

特异性

ZNF384 Polyclonal Antibody detects endogenous levels of ZNF384 protein.

基因名称

ZNF384

蛋白名称

Zinc finger protein 384

别名

ZNF384;CAGH1;CIZ;NMP4;TNRC1;Zinc finger protein 384;CAG repeat protein 1;CAS-interacting zinc finger protein;Nuclear matrix transcription factor 4;Nuclear matrix protein 4;Trinucleotide repeat-containing gene 1 protein

基因ID-1

171017

SwissProt

Q8TF68

背景

zinc finger protein 384(ZNF384) Homo sapiens This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Apr 2011],

细胞定位

Nucleus .