OAS2 Polyclonal Antibody

产品详情

产品名称

OAS2 Polyclonal Antibody

产品货号

YM-A21476

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

WB,IHC,IF,ELISA

分子量

82kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:20000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from the N-terminal region of human OAS2. AA range:61-110

特异性

OAS2 Polyclonal Antibody detects endogenous levels of OAS2 protein.

基因名称

OAS2

蛋白名称

2'-5'-oligoadenylate synthase 2

别名

OAS2;2'-5'-oligoadenylate synthase 2;2-5';oligo;A;synthase 2;2-5A synthase 2;p69 OAS / p71 OAS;p69OAS / p71OAS

基因ID-1

4939

SwissProt

P29728

背景

2'-5'-oligoadenylate synthetase 2(OAS2) Homo sapiens This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],

细胞定位

Cytoplasm . Cytoplasm, perinuclear region .