CD85d Polyclonal Antibody

产品详情

产品名称

CD85d Polyclonal Antibody

产品货号

YM-A21523

规格

50μL;100μL

种属反应

Human

实验应用

WB,ELISA

分子量

66kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from the Internal region of human LILRB2. AA range:121-170

特异性

CD85d Polyclonal Antibody detects endogenous levels of CD85d protein.

基因名称

LILRB2

蛋白名称

Leukocyte immunoglobulin-like receptor subfamily B member 2

别名

LILRB2;ILT4;LIR2;MIR10;Leukocyte immunoglobulin-like receptor subfamily B member 2;LIR-2;Leukocyte immunoglobulin-like receptor 2;CD85 antigen-like family member D;Immunoglobulin-like transcript 4;ILT-4;Monocyte/macrophage immunoglobulin-like receptor 10;MIR-10;CD85d

基因ID-1

10288

SwissProt

Q8N423

背景

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

细胞定位

Cell membrane ; Single-pass type I membrane protein.