BST-2 Polyclonal Antibody

产品详情

产品名称

BST-2 Polyclonal Antibody

产品货号

YM-A21537

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

WB,IHC,IF,ELISA

分子量

20kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:10000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from the Internal region of human BST2. AA range:101-150

特异性

BST-2 Polyclonal Antibody detects endogenous levels of BST-2 protein.

基因名称

BST2

蛋白名称

Bone marrow stromal antigen 2

别名

BST2;Bone marrow stromal antigen 2;BST-2;HM1.24 antigen;Tetherin;CD317

基因ID-1

684

SwissProt

Q10589

背景

Bone marrow stromal cells are involved in the growth and development of B-cells. The specific function of the protein encoded by the bone marrow stromal cell antigen 2 is undetermined; however, this protein may play a role in pre-B-cell growth and in rheumatoid arthritis. [provided by RefSeq, Jul 2008],

细胞定位

Golgi apparatus, trans-Golgi network. Cell membrane ; Single-pass type II membrane protein. Cell membrane ; Lipid-anchor, GPI-anchor . Membrane raft. Cytoplasm. Apical cell membrane . Shuttles between the cell membrane, where it is present predominantly in membrane/lipid rafts, and the trans-Golgi network. Forms a complex with MMP14 and localizes to the cytoplasm.; Golgi apparatus, trans-Golgi network . Late endosome . (Microbial infection) HIV-1 VPU and HIV-2 ENV can target it to the trans-Golgi network thus sequestering it away from virus assembly sites on the cell membrane. Targeted to late endosomes upon KSHV infection and subsequent ubiquitination. .