Lambda 5 Polyclonal Antibody

产品详情

产品名称

Lambda 5 Polyclonal Antibody

产品货号

YM-A21562

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,IHC,IF,ELISA

分子量

23kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:10000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from the C-terminal region of human IGLL1. AA range:151-200

特异性

Lambda 5 Polyclonal Antibody detects endogenous levels of Lambda 5 protein.

基因名称

IGLL1

蛋白名称

Immunoglobulin lambda-like polypeptide 1

别名

IGLL1;IGL1;Immunoglobulin lambda-like polypeptide 1;CD179 antigen-like family member B;Ig lambda-5;Immunoglobulin omega polypeptide;Immunoglobulin-related protein 14.1;CD179b

基因ID-1

3543

SwissProt

P15814

背景

immunoglobulin lambda like polypeptide 1(IGLL1) Homo sapiens The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

细胞定位

Endoplasmic reticulum . Secreted . In pre-B cells, localizes predominantly to the endoplasmic reticulum. .