Lefty Polyclonal Antibody

产品详情

产品名称

Lefty Polyclonal Antibody

产品货号

YM-A21568

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,IHC

分子量

40kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;IHC 1:50-300

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from the C-terminal region of human LEFTY1/LEFTY2. AA range:301-350

特异性

Lefty Polyclonal Antibody detects endogenous levels of Lefty protein.

基因名称

LEFTY1/LEFTY2

蛋白名称

Left-right determination factor 1/Left-right determination factor 2

别名

LEFTY1;LEFTB;LEFTYB;Left-right determination factor 1;Left-right determination factor B;Protein lefty-1;Protein lefty-B;LEFTY2;EBAF;LEFTA;LEFTYA;TGFB4;PSEC0024;Left-right determination factor 2;Endometrial bleeding-associated factor;Left-right determination factor A;Protein lefty-2;Protein lefty-A;Transforming growth factor beta-4;TGF-beta-4

基因ID-1

10637;7044

SwissProt

O75610;O00292

背景

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in left-right asymmetry determination of organ systems during development. This gene is closely linked to both a related family member and a related pseudogene. [provided by RefSeq, Aug 2016],

细胞定位

Secreted.