BMP-15 Polyclonal Antibody

产品详情

产品名称

BMP-15 Polyclonal Antibody

产品货号

YM-A21571

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,IHC,IF,ELISA

分子量

45kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

IHC: 100-300;WB 1:500-1:2000;ELISA 1:10000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from the Internal region of human BMP15. AA range:291-340

特异性

BMP-15 Polyclonal Antibody detects endogenous levels of BMP-15 protein.

基因名称

BMP15

蛋白名称

Bone morphogenetic protein 15

别名

BMP15;GDF9B;Bone morphogenetic protein 15;BMP-15;Growth/differentiation factor 9B;GDF-9B

基因ID-1

9210

SwissProt

O95972

背景

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate subunits of a disulfide-linked homodimer, or alternatively, a heterodimer, with the related protein, growth differentiation factor 9 (GDF9). This protein plays a role in oocyte maturation and follicular development, through activation of granulosa cells. Defects in this gene are the cause of ovarian dysgenesis and are associated with premature ovarian failure. [provided by RefSeq, Aug 2016],

细胞定位

Secreted.