PI 3-Kinase C2γ Polyclonal Antibody

产品详情

产品名称

PI 3-Kinase C2γ Polyclonal Antibody

产品货号

YM-A21602

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

WB,IHC

分子量

160kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;IHC 1:50-300

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from the N-terminal region of human PI 3-Kinase C2γ.

特异性

PI 3-Kinase C2γ Polyclonal Antibody detects endogenous levels of PI 3-Kinase C2γ protein.

基因名称

PIK3C2G

蛋白名称

Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma

别名

PIK3C2G;Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma;PI3K-C2-gamma;PtdIns-3-kinase C2 subunit gamma;Phosphoinositide 3-kinase-C2-gamma

基因ID-1

5288

SwissProt

O75747

背景

The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. This gene may play a role in several diseases, including type II diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],

细胞定位

Membrane ; Peripheral membrane protein .