TP53INP2 Polyclonal Antibody

产品详情

产品名称

TP53INP2 Polyclonal Antibody

产品货号

YM-A21640

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

WB,IHC,IF,ELISA

分子量

24kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:10000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from the C-terminal region of human TP53INP2. AA range:161-210

特异性

TP53INP2 Polyclonal Antibody detects endogenous levels of TP53INP2 protein.

基因名称

TP53INP2

蛋白名称

Tumor protein p53-inducible nuclear protein 2

别名

TP53INP2;C20orf110;DOR;PINH;Tumor protein p53-inducible nuclear protein 2;Diabetes and obesity-regulated gene;p53-inducible protein U;PIG-U

基因ID-1

58476

SwissProt

Q8IXH6

背景

tumor protein p53 inducible nuclear protein 2(TP53INP2) Homo sapiens The protein encoded by this gene promotes autophagy and is essential for proper autophagosome formation and processing. In addition, the encoded protein can enhance rDNA transcription by helping in the assembly of the POLR1/RNA polymerase I preinitiation complex. Finally, this protein serves as a transcriptional activator for some genes. [provided by RefSeq, Jul 2016],

细胞定位

Cytoplasm, cytosol. Nucleus. Nucleus, PML body. Cytoplasmic vesicle, autophagosome. Shuttles between the nucleus and the cytoplasm, depending on cellular stress conditions, and re-localizes to autophagosomes on autophagy activation.