PI 3 Kinase Class 3 Polyclonal Antibody

产品详情

产品名称

PI 3 Kinase Class 3 Polyclonal Antibody

产品货号

YM-A21661

规格

50μL;100μL

种属反应

Human,Mouse,Rat,Cow,Pig,

实验应用

WB,IHC

分子量

100kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;IHC 1:50-300

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthetic Peptide of PI 3 Kinase Class 3

特异性

This antibody detects endogenous levels of PI 3 Kinase Class 3 Polyclonal Antibody at Human;Mouse;Rat;Predicted:Cow:PIG

基因名称

PIK3C3 VPS34

蛋白名称

PI 3 Kinase Class 3

别名

phosphoinositide-3-kinase, class 3

基因ID-1

5289

SwissProt

Q8NEB9

背景

catalytic activity:ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate.,cofactor:Manganese.,function:Catalytic subunit of the PI3K complex. Involved in the transport of lysosomal enzyme precursors to lysosomes.,similarity:Belongs to the PI3/PI4-kinase family.,similarity:Contains 1 PI3K/PI4K domain.,subunit:Probably forms a complex with AMBRA1 and BECN1 (By similarity). Heterodimer. This subunit, part of a complex composed of regulatory and catalytic subunits, associates with regulatory subunit PIK3R4.,tissue specificity:Ubiquitously expressed, with a highest expression in skeletal muscle.,

细胞定位

Midbody . Late endosome . Cytoplasmic vesicle, autophagosome . As component of the PI3K complex I localized to pre-autophagosome structures. As component of the PI3K complex II localized predominantly to endosomes (PubMed:14617358). Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme (By similarity). .