Tryptase-3 Polyclonal Antibody

产品详情

产品名称

Tryptase-3 Polyclonal Antibody

产品货号

YM-A21672

规格

50μL;100μL

种属反应

Human

实验应用

WB,ELISA

分子量

26kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;ELISA 1:10000-20000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from Tryptase-3 at AA range: 51-100

特异性

Tryptase-3 Polyclonal Antibody detects endogenous levels of Tryptase-3

基因名称

TPSD1

蛋白名称

Tryptase-3

别名

Tryptase delta;Delta-tryptase;HmMCP-3-like tryptase III;Mast cell mMCP-7-like;Tryptase-3;

基因ID-1

23430

SwissProt

Q9BZJ3

背景

tryptase delta 1(TPSD1) Homo sapiens Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. Although this gene may be an exception, most of the tryptase genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and

细胞定位

Secreted . Released from the secretory granules upon mast cell activation. .