ETBR Polyclonal Antibody

产品详情

产品名称

ETBR Polyclonal Antibody

产品货号

YM-A21680

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

WB,IHC,IF,ELISA

分子量

50kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

IHC: 100-300;WB 1:500-2000;ELISA 1:10000-20000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from ETBR at AA range: 31-80

特异性

ETBR Polyclonal Antibody detects endogenous levels of ETBR

基因名称

EDNRB

蛋白名称

ETBR

别名

Endothelin B receptor;ET-B;ET-BR;Endothelin receptor non-selective type;

基因ID-1

1910

SwissProt

P24530

背景

The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016],

细胞定位

Cell membrane ; Multi-pass membrane protein. internalized after activation by endothelins. .