ASIC1 Polyclonal Antibody

产品详情

产品名称

ASIC1 Polyclonal Antibody

产品货号

YM-A21746

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IF,IHC-f,ELISA

分子量

70-75kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;IHC 1:500-200;ELISA 1:10000-20000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthetic peptide from human protein at AA range: 220-280

特异性

The antibody detects endogenous ASIC1

基因名称

ASIC1 ACCN2 BNAC2

蛋白名称

Acid-sensing ion channel 1 (ASIC1) (Amiloride-sensitive cation channel 2, neuronal) (Brain sodium channel 2) (BNaC2)

别名

Acid-sensing ion channel 1;ASIC1;Amiloride-sensitive cation channel 2, neuronal;Brain sodium channel 2;BNaC2;

基因ID-1

41

SwissProt

P78348

背景

This gene encodes a member of the acid-sensing ion channel (ASIC) family of proteins, which are part of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Members of the ASIC family are sensitive to amiloride and function in neurotransmission. The encoded proteins function in learning, pain transduction, touch sensation, and development of memory and fear. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012],

细胞定位

Cell membrane ; Multi-pass membrane protein . Localizes in synaptosomes at dendritic synapses of neurons. Colocalizes with DLG4 (By similarity). .