CD218b Polyclonal Antibody

产品详情

产品名称

CD218b Polyclonal Antibody

产品货号

YM-A21797

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

IHC,IF,ELISA

分子量

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

IHC 1:50-200;ELISA 1:10000-20000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthetic peptide from human protein at AA range: 291-340

特异性

The antibody detects endogenous CD218b

基因名称

IL18RAP IL1R7

蛋白名称

Interleukin-18 receptor accessory protein (IL-18 receptor accessory protein) (IL-18RAcP) (Accessory protein-like) (AcPL) (CD218 antigen-like family member B) (CDw218b) (IL-1R accessory protein-like) (IL-1RAcPL) (Interleukin-1 receptor 7) (IL-1R-7) (IL-1R7) (Interleukin-18 receptor accessory protein-like) (Interleukin-18 receptor beta) (IL-18R-beta) (IL-18Rbeta) (CD antigen CD218b)

别名

Interleukin-18 receptor accessory protein;IL-18 receptor accessory protein;IL-18RAcP;Accessory protein-like;AcPL;CD218 antigen-like family member B;CDw218b;IL-1R accessory protein-like;IL-1RAcPL;Interleukin-1 receptor 7;IL-1R-7;IL-1R7;Interleukin-18 receptor accessory protein-like;Interleukin-18 receptor beta;IL-18R-beta;IL-18Rbeta;CD antigen CD218b;

基因ID-1

8807

SwissProt

O95256

背景

The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for interleukin 18 (IL18), a proinflammatory cytokine involved in inducing cell-mediated immunity. This protein enhances the IL18-binding activity of the IL18 receptor and plays a role in signaling by IL18. Mutations in this gene are associated with Crohn's disease and inflammatory bowel disease, and susceptibility to celiac disease and leprosy. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014],

细胞定位

Cell membrane ; Single-pass type I membrane protein .