BMPR-IB Polyclonal Antibody

产品详情

产品名称

BMPR-IB Polyclonal Antibody

产品货号

YM-A21884

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

IHC,IF,ELISA

分子量

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

IHC 1:50-200;ELISA 1:10000-20000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthetic peptide from human protein at AA range: 21-70

特异性

The antibody detects endogenous BMPR-IB

基因名称

BMPR1B

蛋白名称

Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (CD antigen CDw293)

别名

Bone morphogenetic protein receptor type-1B;BMP type-1B receptor;BMPR-1B;CD antigen CDw293;

基因ID-1

658

SwissProt

O00238

背景

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for thi

细胞定位

Cell membrane ; Single-pass type I membrane protein .