NAIP Polyclonal Antibody

产品详情

产品名称

NAIP Polyclonal Antibody

产品货号

YM-A21899

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

IHC,IF,ELISA

分子量

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

IHC 1:50-200;ELISA 1:10000-20000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthetic peptide from human protein at AA range: 1191-1240

特异性

The antibody detects endogenous NAIP

基因名称

NAIP BIRC1

蛋白名称

Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein)

别名

Baculoviral IAP repeat-containing protein 1;Neuronal apoptosis inhibitory protein;

基因ID-1

4671

SwissProt

Q13075

背景

This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length; additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1. The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by Ref

细胞定位

cytoplasm,basolateral plasma membrane,neuron projection,perikaryon,extracellular exosome,