LIM and SH3 domain protein 1 Polyclonal Antibody

产品详情

产品名称

LIM and SH3 domain protein 1 Polyclonal Antibody

产品货号

YM-A21912

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC

分子量

38kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;IHC 1:50-300

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human LIM and SH3 domain protein 1. at AA range: 90-130

特异性

This antibody detects endogenous levels of LIM and SH3 domain protein 1

基因名称

LASP1 MLN50

蛋白名称

LIM and SH3 domain protein 1

别名

LIM and SH3 domain protein 1;LASP-1;Metastatic lymph node gene 50 protein;MLN 50;

基因ID-1

3927

SwissProt

Q14847

背景

This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer. [provided by RefSeq, Oct 2012],

细胞定位

Cytoplasm, cell cortex . Cytoplasm, cytoskeleton . Associated with the F-actin rich cortical cytoskeleton. .