Tropomyosin α Polyclonal Antibody

产品详情

产品名称

Tropomyosin α Polyclonal Antibody

产品货号

YM-A21921

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,ELISA

分子量

38kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;ELISA 1:10000-20000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human Tropomyosin α. at AA range: 101-150

特异性

Tropomyosin α Polyclonal Antibody detects endogenous levels of Tropomyosin α

基因名称

TPM1

蛋白名称

Tropomyosin α

别名

Tropomyosin alpha-1 chain;Alpha-tropomyosin;Tropomyosin-1;

基因ID-1

7168

SwissProt

P09493

背景

This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy. [provided by

细胞定位

Cytoplasm, cytoskeleton . Associates with F-actin stress fibers. .