TRY2 Polyclonal Antibody

产品详情

产品名称

TRY2 Polyclonal Antibody

产品货号

YM-A21990

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

IHC,IF,WB

分子量

27kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

IHC 1:50-200;WB 1:500-2000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human TRY2

特异性

This antibody detects endogenous levels of human TRY2

基因名称

PRSS2 TRY2 TRYP2

蛋白名称

TRY2

别名

Trypsin-2;Anionic trypsinogen;Serine protease 2;Trypsin II;

基因ID-1

5645

SwissProt

P07478

背景

This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2015],

细胞定位

Secreted, extracellular space.