Cyclin T2 Polyclonal Antibody

产品详情

产品名称

Cyclin T2 Polyclonal Antibody

产品货号

YM-A22020

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

IHC,IF,WB

分子量

73kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

IHC 1:50-200;WB 1:500-2000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human Cyclin T2 AA range: 510-590

特异性

This antibody detects endogenous levels of human Cyclin T2

基因名称

CCNT2

蛋白名称

Cyclin T2

别名

Cyclin-T2;CycT2;

基因ID-1

905

SwissProt

O60583

背景

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. A pseudogene of this gene is found on chromosome 1. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010],

细胞定位

Cytoplasm, perinuclear region . Nucleus . Nucleus in differentiating cells. .