POLD4 Polyclonal Antibody

产品详情

产品名称

POLD4 Polyclonal Antibody

产品货号

YM-A22039

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,IHC,IF,ELISA

分子量

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human POLD4 AA range: 43-93

特异性

This antibody detects endogenous levels of human POLD4

基因名称

POLD4 POLDS

蛋白名称

POLD4

别名

DNA polymerase delta subunit 4;DNA polymerase delta subunit p12;

基因ID-1

57804

SwissProt

Q9HCU8

背景

This gene encodes the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012],

细胞定位

Nucleus . Partially recruited to DNA damage sites within 2 hours following UV irradiation, before degradation. .