DYL1 rabbit pAb

产品详情

产品名称

DYL1 rabbit pAb

产品货号

YM-A22964

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

IHC,IF

分子量

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

IHC 1:50-200;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human DYL1 AA range: 1-50

特异性

This antibody detects endogenous levels of DYL1 at Human/Mouse/Rat

基因名称

DYNLL1 DLC1 DNCL1 DNCLC1 HDLC1

蛋白名称

DYL1

别名

基因ID-1

8655

SwissProt

P63167

背景

Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008],

细胞定位

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton . Nucleus . Mitochondrion . Upon induction of apoptosis translocates together with BCL2L11 to mitochondria. .