PLOD1 rabbit pAb

产品详情

产品名称

PLOD1 rabbit pAb

产品货号

YM-A23204

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,ELISA,IHC

分子量

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human PLOD1 AA range: 551-601

特异性

This antibody detects endogenous levels of PLOD1 at Human/Mouse/Rat

基因名称

PLOD1 LLH PLOD

蛋白名称

PLOD1

别名

基因ID-1

5351

SwissProt

Q02809

背景

Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015],

细胞定位

Rough endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side.