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产品详情
产品名称
GLYM rabbit pAb
产品货号
YM-A23315
规格
50μL;100μL
种属反应
Human,Mouse
实验应用
WB
分子量
宿主
Rabbit
同种型
IgG
修饰
Unmodified
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克降性
Polyclonal
克隆号
免疫原
Synthesized peptide derived from human GLYM AA range: 122-172
特异性
This antibody detects endogenous levels of GLYM at Human
基因名称
SHMT2
蛋白名称
GLYM
别名
基因ID-1
6472
SwissProt
P34897
背景
This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],
细胞定位
Mitochondrion . Mitochondrion matrix, mitochondrion nucleoid . Mitochondrion inner membrane . Cytoplasm . Nucleus . Mainly localizes in the mitochondrion. Also found in the cytoplasm and nucleus as part of the BRISC complex (PubMed:24075985). .
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