RN139 rabbit pAb

产品详情

产品名称

RN139 rabbit pAb

产品货号

YM-A23445

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,IHC

分子量

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;IHC 1:50-300

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human RN139 AA range: 10-60

特异性

This antibody detects endogenous levels of RN139 at Human/Mouse

基因名称

RNF139 TRC8

蛋白名称

RN139

别名

基因ID-1

11236

SwissProt

Q8WU17

背景

The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP. [provided by RefSeq, Jul 2008],

细胞定位

Endoplasmic reticulum membrane ; Multi-pass membrane protein .