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产品详情
产品名称
GLIS3 rabbit pAb
产品货号
YM-A23561
规格
50μL;100μL
种属反应
Human,Mouse
实验应用
WB
分子量
宿主
Rabbit
同种型
IgG
修饰
Unmodified
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克降性
Polyclonal
克隆号
免疫原
Synthesized peptide derived from human GLIS3 AA range: 381-431
特异性
This antibody detects endogenous levels of GLIS3 at Human/Mouse
基因名称
GLIS3 ZNF515
蛋白名称
GLIS3
别名
基因ID-1
169792
SwissProt
Q8NEA6
背景
This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear protein with five C2H2-type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only two have been determined. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus .
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