PD-1 rabbit pAb

产品详情

产品名称

PD-1 rabbit pAb

产品货号

YM-A23621

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,ELISA,IHC

分子量

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human Pdcd-1 AA range: 80-130

特异性

This antibody detects endogenous levels of Human Pdcd-1

基因名称

PDCD1 PD1

蛋白名称

Pdcd-1

别名

Programmed cell death protein 1;Protein PD-1;hPD-1;CD antigen CD279;

基因ID-1

5133

SwissProt

Q15116

背景

This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008],

细胞定位

Cell membrane ; Single-pass type I membrane protein.