RFA1 rabbit pAb

产品详情

产品名称

RFA1 rabbit pAb

产品货号

YM-A23732

规格

50μL;100μL

种属反应

Human,Monkey,Mouse,Rat

实验应用

WB,ELISA,IHC

分子量

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human RFA1

特异性

This antibody detects endogenous levels of Human,Monkey,Mouse,Rat RFA1

基因名称

RPA1 REPA1 RPA70

蛋白名称

RFA1

别名

Replication protein A 70 kDa DNA-binding subunit;RP-A p70;Replication factor A protein 1;RF-A protein 1;Single-stranded DNA-binding protein;

基因ID-1

6117

SwissProt

P27694

背景

function:It participates in a very early step in initiation. RP-A is a single-stranded DNA-binding protein. Absolutely required for simian virus 40 DNA replication in vitro.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the replication factor A protein 1 family.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Interacts with RIP and XPA. Interacts with RPA4.,

细胞定位

Nucleus . Nucleus, PML body . Enriched in PML bodies in cells displaying alternative lengthening of their telomeres. .